Description
This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field undergraduates, engineers, biologists, medical researcherswill easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications. Chapter 1: Acoustofluidic blood component sample preparation and processing in medical applications Maria Antfolk and Thomas Laurell Chapter 2: Microfluidic technologies and platforms for protein crystallography Masatoshi Maeki and Manabu Tokeshi Chapter 3: Application of Sers-based Microfluidics for in Vitro Diagnostics Jinhyeok Jeon, Namhyun Choi, Joung-Il Moon, Hao Chen and Jaebum Choo Chapter 4: Miniaturized Electrochemical Sensors to Facilitate Liquid Biopsy for Detection of Circulating Tumor Markers Yi-Ge Zhou, Leyla Kermanshah, Libing Zhang and Reza M. Mohamadi Chapter 5: Spiral Inertial Microfluidics for Cell Separation and Biomedical Applications Ning Liu, Chayakorn Petchakup, Hui Min Tay, King Ho Holden Li and Han Wei Hou Chapter 6: Worms on a Chip Han-Sheng Chuang, Wen-Hui Wang, Chang-Shi Chen Chapter 7: Microfluidic devices for gamete processing and analysis, fertilization and embryo culture and characterization Sverine Le Gac, Verena Nordhoff, Bastien Venzac Chapter 8: Microfluidic organs-on-chips to reconstitute cellular microenvironments Yu-suke Torisawa Chapter 9: In vitro tissue construction for organ-on-a-chip applications Yuya Morimoto, Nobuhito Mori and Shoji Takeuchi Chapter 10: Nanobiodevices for Cancer Diagnostics and Stem Cell Therapeutics D. Onoshima, H. Yukawa and Y. Baba Chapter 11: Nanopore Device for Single-Molecule Sensing Method and Its Application Masateru Taniguchi and Takahito Ohshiro Chapter 12: Paper Microfluidics for POC Testing in Low-resource Settings Elain Fu Chapter 13: Paper-Based Microfluidics for Point-of-Care Medical Diagnostics Kentaro Yamada and Daniel Citterio
